Levels of 1-hydroxypyrene as a biological marker for polycyclic aromatic hydrocarbons exposure in the Mexican population

Julia D. Torres-Garza, Departamento de Farmacología y Toxicología, Facultad de Medicina, UANL, Nuevo León, Monterrey, Mexico
Christian T. Badillo-Castañeda, Departamento de Farmacología y Toxicología, Facultad de Medicina, Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, Mexico
Lourdes Garza-Ocañas, Departamento de Farmacología y Toxicología, Facultad de Medicina, UANL, Monterrey, Nuevo León, Mexico

Polycyclic aromatic hydrocarbons (PAHs) are pollutants produced during the incomplete combustion of organic materials and are linked to carcinogenic and mutagenic effects. 1-hydroxypyrene (1-OHP) serves as a biomarker for assessing PAH exposure and is recognized as a reliable indicator due to its correlation with PAH levels in both occupational and urban settings. This study aims to review the scientific evidence concerning 1-OHP excretion levels as a biomarker of PAH exposure in the Mexican population.

Keywords: 1-hydroxypyrene. Polycyclic aromatic hydrocarbons. Mexican population.