Consuelo Mancías-Guerra, Servicio de Hematología del Hospital Universitario “Dr. José Eleuterio González” de la Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, México
Laura M. Nuño-Vázquez, Servicio de Hematología del Hospital Universitario “Dr. José Eleuterio González” de la Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, México
Cesar H. Gutiérrez-Aguirre, Servicio de Hematología del Hospital Universitario “Dr. José Eleuterio González” de la Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, México
Olga G. Cantú-Rodríguez, Servicio de Hematología del Hospital Universitario “Dr. José Eleuterio González” de la Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, México
Samantha Fierro-Sáenz, Servicio de Hematología del Hospital Universitario “Dr. José Eleuterio González” de la Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, México
Ileana Velasco-Ruiz, Servicio de Hematología del Hospital Universitario “Dr. José Eleuterio González” de la Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, México
Julia E. Colunga-Pedraza, Servicio de Hematología del Hospital Universitario “Dr. José Eleuterio González” de la Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, México
Valentine Jiménez-Antolinez, Servicio de Hematología del Hospital Universitario “Dr. José Eleuterio González” de la Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, México
Óscar González-Llano, Servicio de Hematología del Hospital Universitario “Dr. José Eleuterio González” de la Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, México
Objective. It has been reported that breastfeeding for 6 and 12 months reduced 20% and 27% of the risk of childhood leukemia, respectively. We present the results of a case–control study about breastfeeding and B-cell acute lymphoblastic leukemia (B-cell ALL) risk in a Mexican pediatric population. Patients and methods. We conducted a case–control study, and a 20-question survey was applied to the patient’s parents. A patient was considered to have been nursed if they received at least 1 month of breastfeeding. For the control group, patients who attended our hospital’s Healthy Child Care Clinic were consecutively selected. Results. The absence of breastfeeding was associated with an odds ratios (OR) of 2.7 for the further development of B-cell ALL. For the subsequent presence of malignancy, the group with 0-1 month of lactation showed an OR of 3.1 compared to the group with more than 6 months of breastfeeding. Conclusions. In the present study, the absence of breastfeeding in our population was associated with an increased risk for the further development of B-cell ALL. Furthermore, it was found that a lower risk for later development of B-cell ALL in their offspring was associated with a lower maternal age.
Keywords: Acute lymphoblastic leukemia. Childhood. Breastfeeding exclusive.